The long non-coding RNA LSINCT5 promotes malignancy in non-small cell lung cancer by stabilizing HMGA2
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چکیده
منابع مشابه
Long Non-coding RNA ZEB1-AS1 Promotes Tumorigenesis and Metastasis in Colorectal Cancer
Emerging evidence implicates that a large fraction of human genome was transcribed but the transcripts known as long non coding RNA are not translated into proteins. They are contributing in different cellular processes, including cellular proliferation and apoptosis. LncRNAs were found to play critical roles in many diseases and act as key regulators in malignancies. In this study, we investig...
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Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer. The abnormal expression of many long non-coding RNAs (lncRNAs) has been reported involved in the progression of various tumours, which can be used as diagnostic indicators or antitumour targets. Here, we found that the long non-coding RNA 00312 was down-regulated in paired NSCLC tissues and correlated with poor clinic...
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Objective(s): Lung cancer is one of the most common malignant tumors, which seriously threatens the health and life of the people. Recently, a novel long non-coding RNA (lncRNA) termed lncFOXO1 was found and investigated in breast cancer. However, the effect of lncFOXO1 on lung cancer is still ambiguous. The current study aimed to uncover the functions of lncFOXO1 in l...
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Background: Despite recent advances in diagnosis and treatment, breast cancer remains a leading cause of death in women worldwide. Long non-coding RNAs are a new class of RNA molecules that have been shown to participate in tumorigenesis. The aim of this study was to investigate the expression of lncUSMycN in tumor samples and to evaluate its potential role in the breast cancer cell line. Metho...
متن کاملLong non-coding RNA Loc344887 is a potential prognostic biomarker in non-small cell lung cancer.
OBJECTIVE Long non-coding RNA NmrA-like family domain containing 1 pseudogene (Loc344887) has been shown to be aberrantly expressed in non-small cell lung cancer (NSCLC). However, the biological function of Loc344887 in NSCLC remains unknown. The present study aimed to explore the prognosis value of Loc344887 in NSCLC patients. PATIENTS AND METHODS Quantitative reverse transcription-polymeras...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2018
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2018.1467675